Joint effects of triglyceride glucose index and its obesity-related derivatives with estimated glucose disposal rate on cardiometabolic multimorbidity in middle-aged and older Chinese adults: a nationwide cohort study
High TyG-related indices and low eGDR were independently and jointly associated with higher CMM risk. Joint application of TyG-related indices and eGDR could improve early identification and prevention of CMM.
Authors
- Xin Gao (ORCID: https://orcid.org/0000-0002-5160-1725)
- Shiqun Chen (ORCID: https://orcid.org/0000-0002-2847-019X)
- Yibo He (ORCID: https://orcid.org/0000-0003-3777-9516)
- Jinming Chen (ORCID: https://orcid.org/0000-0002-0594-0646)
- Tian Chang
- Xiaozhao Lu
- Junyan Xu (ORCID: https://orcid.org/0000-0001-7772-0469)
- Ling Jing (ORCID: https://orcid.org/0000-0002-4919-8121)
- Weipeng Zhang
- Yihang Ling
- Xianlin Ruan
- Yulong Xiang
- Huangtao Ruan
Institutions
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12933-025-02939-7
- Citations
- 12
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 15.54
Funders
- AstraZeneca
- National Natural Science Foundation of China
- Guangdong Medical Research Foundation
- Peking University
- Guangdong Provincial People's Hospital
- Basic and Applied Basic Research Foundation of Guangdong Province