A Case of Mucogenic Iris Cyst with Ophthalmohypertension Followed by Iridectomy with Iridoplasty

There is a clinical case of mucogenic iris cyst with ocular hypertension. The patient had noticed an iris spot since childhood. At the age of 33, she was diagnosed with iridocorneal syndrome and iris cyst. At the age of 38, an IOP decompensation was the reason for fistulizing surgery. At 41 years, progression of the iris cyst was noted, which was an indication for iridectomy with iridoplasty. According to the histological examination, the cyst wall is presented by sclerotic iris stroma, as well as dense unformed fibrous tissue fused with Descemet's membrane. In the lumen of the cyst, mucous contents are determined with the formation of mucous globules and an admixture of native and hemolyzed erythrocytes, clusters of macrophages with abundant light vacuolated cytoplasm. The inner surface of the cyst is lined with mature multi-row cylindrical intestinal-type epithelium and numerous goblet cells.

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Journal
Ophthalmology in Russia
Published
2025-10-01
DOI
https://doi.org/10.18008/1816-5095-2025-3-632-637
Primary Topic
Glaucoma and retinal disorders
Type
article
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article

A Case of Mucogenic Iris Cyst with Ophthalmohypertension Followed by Iridectomy with Iridoplasty

Н. С. Измаилова, Sergey Yu. Petrov, А. А. Жаров, Р. А. Тацков et al.
Ophthalmology in Russia
Glaucoma and retinal disorders
article

A Case of Mucogenic Iris Cyst with Ophthalmohypertension Followed by Iridectomy with Iridoplasty

Н. С. Измаилова, Sergey Yu. Petrov, А. А. Жаров, Р. А. Тацков, Ольга Викторовна Пантелеева, Svetlana Vladimirovna Saakyan
article en

Abstract

There is a clinical case of mucogenic iris cyst with ocular hypertension. The patient had noticed an iris spot since childhood. At the age of 33, she was diagnosed with iridocorneal syndrome and iris cyst. At the age of 38, an IOP decompensation was the reason for fistulizing surgery. At 41 years, progression of the iris cyst was noted, which was an indication for iridectomy with iridoplasty. According to the histological examination, the cyst wall is presented by sclerotic iris stroma, as well as dense unformed fibrous tissue fused with Descemet's membrane. In the lumen of the cyst, mucous contents are determined with the formation of mucous globules and an admixture of native and hemolyzed erythrocytes, clusters of macrophages with abundant light vacuolated cytoplasm. The inner surface of the cyst is lined with mature multi-row cylindrical intestinal-type epithelium and numerous goblet cells.

Ophthalmology in RussiaVol. 22(3)
Moscow State University of Medicine and Dentistry (RU), Helmholtz Moscow Research Institute of Eye Diseases (RU)
Openalex Percentile: Top 60%
Glaucoma and retinal disorders
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