Construction of diagnostic model and subtype analysis of major depressive disorder based on PANoptosis key genes
This study established a PANoptosis-based diagnostic framework for MDD and identified PANoptosis-stratified MDD subtypes, providing compelling evidence for PANoptosis-mediated immune dysregulation in MDD pathogenesis. These results offered a novel perspective for the diagnosis and management of MDD.
Authors
- Na Huang (ORCID: https://orcid.org/0000-0001-6522-0221)
- Xinxin Ma (ORCID: https://orcid.org/0000-0002-1806-6599)
- Huan Zhang (ORCID: https://orcid.org/0009-0009-1420-0154)
- Yanan Liu (ORCID: https://orcid.org/0000-0001-9625-5806)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12888-025-07397-9
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58