In vitro cytokine response of circulating mononuclear cells from healthy dogs to stage-specific antigens of Angiostrongylus vasorum
Distinct cytokine profiles elicited by different A. vasorum antigens suggest that the parasite's modulation of host immunity and induction of stage-specific responses are key to persistence and clinical presentation of canine angiostrongylosis. Further investigation into the antigenic components and immune pathways may lead to tailored therapies, improved clinical management, and to a deeper understanding of stage-specific aspects of helminth infections.
Authors
- Andreas W. Oehm (ORCID: https://orcid.org/0000-0002-2709-8541)
- Salomé LeibundGut‐Landmann (ORCID: https://orcid.org/0000-0002-5724-4837)
- Ulisse Salazar (ORCID: https://orcid.org/0009-0008-8041-3222)
- Manuela Schnyder (ORCID: https://orcid.org/0000-0002-6523-7952)
- Johannes vom Berg (ORCID: https://orcid.org/0000-0002-4086-1564)
- Janine Hertaeg
Institutions
- University of Bern (CH)
- University of Zurich (CH)
- University of Exeter (GB)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12917-025-04977-5
- Citations
- 2
- Primary Topic
- Mollusks and Parasites Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung