Neuro-immune regulation of sepsis-associated delirium via the PBN-CeA-spleen axis
The PBN-CeA-splenic axis plays a critical neuroimmune conduit linking central neural circuits to peripheral immune modulation, offering new mechanistic insight into the neural regulation of systemic inflammation and the pathogenesis of SAD.
Authors
- Qianyi Peng (ORCID: https://orcid.org/0000-0001-5974-466X)
- Zhiwen Ye (ORCID: https://orcid.org/0000-0003-4311-1037)
- Wangyuan Zou (ORCID: https://orcid.org/0000-0003-4813-2806)
- Mingqing Dong (ORCID: https://orcid.org/0000-0001-9720-535X)
- Yuhang Ai (ORCID: https://orcid.org/0000-0001-7682-7782)
- Yu Zou (ORCID: https://orcid.org/0000-0001-5699-5869)
- Lina Zhang (ORCID: https://orcid.org/0009-0004-1234-1379)
Institutions
- Central South University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- National Clinical Research (US)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12974-025-03527-y
- Citations
- 1
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Natural Science Foundation of China