DNA base editors are a promising tool to gene therapy of human viral infections

One of the significant achievements in the field of genomic editing has been the use of base editors. This approach involves the point-by-point editing of nitrogenous bases in the DNA of living cells. Since such an editing method does not involve the introduction of double-stranded breaks, such as the widespread CRISPR-Cas method, base editors are a promising tool in gene therapy by temporarily altering RNA bases or permanently altering DNA bases. Recent advances in the specificity, effectiveness, accuracy, and delivery of base editors open up new therapeutic possibilities for these technologies. It can be assumed that the correction of single nucleotide mutations will become one of the directions of precision medicine of the future.