VH032 suppresses glioma proliferation by inhibiting the VHL/HIF-1α/VEGF pathway
These findings suggest that VH032 is a novel and promising chemotherapeutic agent for gliomas, acting through the interference of the VHL/HIF-1α/VEGF signaling pathway to suppress migration and invasion of glioma cells.
Authors
- Shaozhang Hou
- Jingyu Yang (ORCID: https://orcid.org/0000-0002-7521-7920)
- Yi Zhang (ORCID: https://orcid.org/0000-0003-3419-2461)
- Yuming Wen (ORCID: https://orcid.org/0000-0001-5506-1706)
- Peng Wang (ORCID: https://orcid.org/0000-0002-0102-4544)
- Jianying Gu (ORCID: https://orcid.org/0000-0002-7870-103X)
- Xinyu Zhu (ORCID: https://orcid.org/0009-0003-5767-1120)
Institutions
- Ningxia Medical University (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.bbrep.2025.102254
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00