RELATIONSHIP BETWEEN SOME LABORATORY INDICATORS AND ANTHROPOMETRIC PARAMETERS IN BULGARIAN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Introduction: Diabetes mellitus is becoming a rapidly growing health concern across the world due to the rapidly growing number of patients. The multidisciplinary approach to type 2 Diabetes mellitus (T2DM) requires, along with anthropometric parameters, monitoring of the patient's lipid profile and glycated hemoglobin levels. The purpose of the present study is to study the correlations between the lipid profile indicators, as well as glycated hemoglobin levels, and some anthropometric parameters of Bulgarian patients with T2DM. Material and Methods. The study included 136 males and 212 females with T2DM, divided into two age groups. Anthropometric parameters: waist (WaC) and hip (HiC) circumferences. Calculated indices: Body mass index (BMI) and Waist-hip ratio (WHR). Laboratory indicators: total cholesterol (TCH), triglycerides (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL) and glycated hemoglobin (HbA1c). Results. In the present study, we have found eleven significant correlations between some anthropometric parameters and laboratory indicators in Bulgarian male patients with T2DM. They were the 1st age group 40-60 years: TCH/BMI, TCH/WaC, TCH/WHR, HDL/BMI, HDL/WaC, and LDL/HiC; 2nd age group 61-80 years: TG/BMI, VLDL/BMI, HbA1c/BMI, HbA1c/WaC, and HbA1c/HiC. We found three significant correlations between the anthropometric parameters and laboratory indicators in Bulgarian females with T2DM. They were the 1st age group, 40-60 years: BMI/HbA1c; 2nd age group, 61-80 years: BMI/TCH and BMI/LDL. Conclusion: The number of correlations between the tested anthropometric parameters and laboratory values were greater in male patients than in women with T2DM. Sexual dimorphism in the impact of T2DM has been reported.