Supramolecular Assembly and Interfacial Hydration of Tandem Repeat Dipeptides on 2D Nanomaterials: Insights From 3D‐AFM Measurements and MD Simulations (Small 39/2025)
Bionanomaterials In article number 2501785, Ayhan Yurtsever, Linhao Sun, Yuhei Hayamizu, Takeshi Fukuma, and co-workers investigate Tyr-His (YH) dipeptide tandem repeats assembled on cleaved graphite and MoS2 substrates. The study reveals how 3D hydration shells govern peptide nanoarchitecture assembly, with molecular visualization showing peptides adopt fully extended, linear conformations aligned with specific crystallographic orientations. The lengths of assembled peptides match their unfolded states, including hydration layers.
Authors
- Mehmet Sarıkaya (ORCID: https://orcid.org/0000-0003-3856-6360)
- Fabio Priante (ORCID: https://orcid.org/0000-0001-7052-8570)
- Kazuki Miyata (ORCID: https://orcid.org/0000-0002-1641-2160)
- Sanhanut Kesornsit
- M. Sugiyama (ORCID: https://orcid.org/0000-0002-5745-8261)
- Linhao Sun (ORCID: https://orcid.org/0000-0002-9584-4729)
- Adam Stuart Foster (ORCID: https://orcid.org/0000-0001-5371-5905)
- Yuhei Hayamizu (ORCID: https://orcid.org/0000-0003-1411-9400)
- Katsuhiro Maeda (ORCID: https://orcid.org/0000-0002-5341-8799)
- Keisuke Miyazawa (ORCID: https://orcid.org/0000-0002-5012-8040)
- Takeshi Fukuma (ORCID: https://orcid.org/0000-0001-8971-6002)
- Ayhan Yurtsever
Institutions
- Kanazawa University (JP)
- Life Science Institute (JP)
- Dentsply Sirona (United States) (US)
- Aalto University (FI)
Publication Details
- Journal
- Small
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/smll.70299
- Primary Topic
- Supramolecular Self-Assembly in Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00