Recurrent Reactive Infectious Mucocutaneous Eruption (RIME) in a Pediatric Patient Triggered by Mycoplasma pneumoniae and Enterovirus Coinfection

Reactive infectious mucocutaneous eruption (RIME) is an underrecognized condition often misdiagnosed as Stevens-Johnson syndrome (SJS). We present a case of a 10-year-old boy who presented with fever, cough, painful oral ulcers, and conjunctival injection that progressed to severe mucositis with urethral involvement. This case is notable both for the unusual urethral manifestation and for its association with a rare co-infection by <i>Mycoplasma pneumoniae</i> and enterovirus, attributable to RIME.

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Publication Details

Journal
Cureus
Published
2025-10-02
DOI
https://doi.org/10.7759/cureus.93698
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Recurrent Reactive Infectious Mucocutaneous Eruption (RIME) in a Pediatric Patient Triggered by Mycoplasma pneumoniae and Enterovirus Coinfection

Mohamad B Alebaji, Ratna Basak, Anna Tryfonos, Bhavya Vasantham
Cureus
Immunodeficiency and Autoimmune Disorders
article

Recurrent Reactive Infectious Mucocutaneous Eruption (RIME) in a Pediatric Patient Triggered by Mycoplasma pneumoniae and Enterovirus Coinfection

Mohamad B Alebaji, Ratna Basak, Anna Tryfonos, Bhavya Vasantham
article en

Abstract

Reactive infectious mucocutaneous eruption (RIME) is an underrecognized condition often misdiagnosed as Stevens-Johnson syndrome (SJS). We present a case of a 10-year-old boy who presented with fever, cough, painful oral ulcers, and conjunctival injection that progressed to severe mucositis with urethral involvement. This case is notable both for the unusual urethral manifestation and for its association with a rare co-infection by <i>Mycoplasma pneumoniae</i> and enterovirus, attributable to RIME.

CureusVol. 17(10)
New York City Health and Hospitals Corporation (US), SUNY Downstate Health Sciences University (US), Kings County Hospital Center (US)
Openalex Percentile: Top 71%
Immunodeficiency and Autoimmune Disorders
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