Comprehensive disproportionality analysis of individual case safety reports associated with Janus kinase inhibitors in psoriasis and psoriatic arthritis using the FAERS database
This research offers practical evidence for assessing the safety of JAK inhibitors used in psoriasis and PsA. Since disproportionality analysis serves as a hypothesis-generating approach, the results necessitate further validation in studies with denominator data to assess causal relationships.
Authors
- Kunhong Deng
- Yun Kuang
- Minghui Yin (ORCID: https://orcid.org/0000-0001-9966-9879)
- Chengxian Guo (ORCID: https://orcid.org/0000-0002-6332-6716)
- Chengjun Guo (ORCID: https://orcid.org/0000-0002-1466-2975)
- Junlong Ma (ORCID: https://orcid.org/0000-0003-1949-1201)
- Han Jiang (ORCID: https://orcid.org/0009-0009-6200-2742)
- Longjian Huang (ORCID: https://orcid.org/0000-0003-1858-0368)
- Yuxia Xiang
- Shan Xie
Institutions
- Guangdong University of Technology (CN)
- Central South University (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1629886
- Citations
- 1
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Central South University
- Xiangya Hospital, Central South University