Revealing the anticancer potential of nano-encapsulated graviola extract on tongue carcinoma (SCC154) cell line: targeting the PI3K/AKT/mTOR pathway (in vitro study)
GNPs showed a better impact than GLE in tongue carcinoma therapy, causing cytotoxicity and apoptosis, potentially through the PI3K/AKT/mTOR pathway.
Authors
- Ahmed Abdrabou (ORCID: https://orcid.org/0000-0002-9875-7591)
- Nermeen AbuBakr (ORCID: https://orcid.org/0000-0003-2962-0070)
- Ahmed Basuoni (ORCID: https://orcid.org/0000-0002-2473-6544)
- Amany Hany Mohamed Kamel (ORCID: https://orcid.org/0000-0002-3562-1099)
Institutions
- Cairo University (EG)
- National Research Centre (EG)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12906-025-05113-4
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Development Fund