Transduction Mechanisms for Cold Temperature in Mouse Trigeminal and Vagal Ganglion Neurons Innervating Different Peripheral Organs
The study highlights the differential contribution of TRPM8 and TRPA1 channels to cold sensitivity in somatic and visceral ganglia, establishing a critical role of TRPA1 channels in visceral cold transduction. Finally, cold sensitivity seems fine-tuned to the specific physiological needs of different organs.
Authors
- Katharina Gers‐Barlag (ORCID: https://orcid.org/0000-0003-2836-2831)
- Ana Gómez del Campo (ORCID: https://orcid.org/0000-0003-4898-0186)
- Félix Viana
- Pablo Hernández‐Ortego (ORCID: https://orcid.org/0000-0001-9591-4144)
- Eva Quintero
Institutions
- Instituto de Neurociencias (ES)
Publication Details
- Journal
- Acta Physiologica
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1111/apha.70111
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Generalitat Valenciana
- European Regional Development Fund
- Agencia Estatal de Investigación
- Spanish National Plan for Scientific and Technical Research and Innovation