Synthesis of highly polysubstituted cyclopentadienes through an oxypalladation initiated domino Heck reaction of internal alkynes

An unexpected oxypalladation initiated domino Heck reaction of internal alkynes was developed for the synthesis of various highly polysubstituted cyclopentadienes in moderate to good yields under mild reaction conditions.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-10-02
DOI
https://doi.org/10.1039/d5qo01231g
Primary Topic
Catalytic Cross-Coupling Reactions
Type
article
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article

Synthesis of highly polysubstituted cyclopentadienes through an oxypalladation initiated domino Heck reaction of internal alkynes

Gui‐Fa Su, Zhang‐Wei Liu, Dong‐Liang Mo, Yu Zhao et al.
Organic Chemistry Frontiers
Catalytic Cross-Coupling Reactions
article

Synthesis of highly polysubstituted cyclopentadienes through an oxypalladation initiated domino Heck reaction of internal alkynes

Gui‐Fa Su, Zhang‐Wei Liu, Dong‐Liang Mo, Yu Zhao, Yu‐Feng Liang, Zhi‐Xin Wang, Jie Zhao
article en

Abstract

An unexpected oxypalladation initiated domino Heck reaction of internal alkynes was developed for the synthesis of various highly polysubstituted cyclopentadienes in moderate to good yields under mild reaction conditions.

Organic Chemistry FrontiersVol. 13(1)
Guangxi Normal University (CN)
Openalex Percentile: Top 79%
Catalytic Cross-Coupling Reactions
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