Monitoring Nitric Oxide in Trigeminal Neuralgia Rats with a Cerium Single-Atom Nanozyme Electrochemical Biosensor
. Results demonstrated that NO concentration was associated with the TN onset. Following carbamazepine treatment, NO production from nerves decreased, accompanied by an alleviation of pain. These findings indicate that the biosensor serves as a valuable tool for investigating the pathogenesis of TN and guiding subsequent therapeutic strategies.
Authors
- Fuhua Li (ORCID: https://orcid.org/0000-0002-1021-2002)
- Chunxian Guo (ORCID: https://orcid.org/0000-0002-2603-7181)
- Muzi Xu (ORCID: https://orcid.org/0000-0001-6381-9863)
- Fangxin Hu
- Kangling Tian
Institutions
- Southwest University (CN)
- Shandong University (CN)
- University of Cambridge (GB)
- Suzhou University of Science and Technology (CN)
- Shanghai Ninth People's Hospital (CN)
- Southwest Jiaotong University (CN)
Publication Details
- Journal
- ACS Sensors
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1021/acssensors.5c04286
- Primary Topic
- Advanced Nanomaterials in Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Jiangsu Provincial Department of Education
- Qinglan Project of Jiangsu Province of China
- Engineering and Physical Sciences Research Council
- Natural Science Research of Jiangsu Higher Education Institutions of China