LC-MS/MS Method for Simultaneous Quantification of Three Oxazolidinone Antimicrobials in Human Plasma: Application to Therapeutic Drug Monitoring
This validated LC-MS/MS method enables the simultaneous determination of linezolid, tedizolid, and contezolid in human plasma, rendering it promising for pharmacokinetic studies and TDM, and contributing to optimized patient care in complex therapeutic scenarios.
Authors
- Beibei Liang (ORCID: https://orcid.org/0000-0002-5363-6315)
- Yun Cai (ORCID: https://orcid.org/0000-0001-6687-9984)
- Ying Wang (ORCID: https://orcid.org/0009-0008-3090-2052)
- Na Zhang (ORCID: https://orcid.org/0000-0003-2270-3463)
- Nan Bai (ORCID: https://orcid.org/0000-0002-0604-8887)
Institutions
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/dddt.s547979
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00