Dose–response relationship in patients who received transarterial radioembolization with Y-90 resin microspheres for hepatocellular carcinoma

We demonstrated a strong relationship between absorbed tumor dose and treatment response in HCC patients who received TARE with Y-90 resin microspheres. Delivery of approximately 100 Gy mean absorbed dose to the tumor is needed to achieve a response. Increasing the TAD to ~160 Gy would be expected to result in a complete response.

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Publication Details

Journal
Nuclear Medicine Communications
Published
2025-10-01
DOI
https://doi.org/10.1097/mnm.0000000000002058
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Dose–response relationship in patients who received transarterial radioembolization with Y-90 resin microspheres for hepatocellular carcinoma

Diğdem Kuru Öz, Çiğdem Soydal, Emre Can Çelebioğlu, E Avci et al.
Nuclear Medicine Communications
Hepatocellular Carcinoma Treatment and Prognosis
article

Dose–response relationship in patients who received transarterial radioembolization with Y-90 resin microspheres for hepatocellular carcinoma

Diğdem Kuru Öz, Çiğdem Soydal, Emre Can Çelebioğlu, E Avci, İrem Mesci
article en

Abstract

We demonstrated a strong relationship between absorbed tumor dose and treatment response in HCC patients who received TARE with Y-90 resin microspheres. Delivery of approximately 100 Gy mean absorbed dose to the tumor is needed to achieve a response. Increasing the TAD to ~160 Gy would be expected to result in a complete response.

Nuclear Medicine CommunicationsVol. 47(1)
Ankara University (TR), Society of Nuclear Medicine and Molecular Imaging (US), Institute of Nuclear Physics (UZ)
Openalex Percentile: Top 64%
Hepatocellular Carcinoma Treatment and Prognosis
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