Case Report: Generalized anxiety disorder and hypertension: a bidirectional loop unraveled by integrated management
This case demonstrates thyroidectomy-induced endocrine disruption as a novel trigger in the GAD-HT bidirectional loop. Multimodal therapy targeting shared neurobiological pathways (HPA axis, autonomic regulation, serotonin signaling) effectively breaks this cycle, underscoring the imperative for integrated mental-cardiovascular care in treatment-resistant cases.
Authors
- Junming Chen (ORCID: https://orcid.org/0000-0001-6406-0924)
- Fugui Jiang (ORCID: https://orcid.org/0009-0005-3432-8930)
- Yuxing Yang
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fpsyt.2025.1600910
- Primary Topic
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00