Multi-omics analyses inform mechanisms of immunotherapy response in pancreatic cancer
These findings indicate that immunochemotherapy shows potential for the treatment of advanced PDAC. Our study elucidates the immune landscape associated with PDAC and provides critical insights for the identification of prospective therapeutic targets, which could guide the development of innovative combination immunotherapy strategies.
Authors
- Ge Li (ORCID: https://orcid.org/0009-0004-2709-8148)
- Jinming Cao (ORCID: https://orcid.org/0000-0001-5946-4967)
- Mengyao Wu (ORCID: https://orcid.org/0000-0003-2082-0885)
- Dapeng Li (ORCID: https://orcid.org/0000-0003-2861-3899)
- Kai Chen (ORCID: https://orcid.org/0000-0002-5852-3264)
- Caihua Xu (ORCID: https://orcid.org/0000-0001-5054-5875)
- Meng Shen (ORCID: https://orcid.org/0000-0002-0570-1020)
- Yecheng Li (ORCID: https://orcid.org/0000-0003-3578-3714)
- Mengdan Xu (ORCID: https://orcid.org/0000-0001-9347-0770)
- Wei Li (ORCID: https://orcid.org/0000-0003-3980-1318)
Institutions
- Renji Hospital (CN)
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1673098
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00