Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

Acinic cell carcinoma (AciCC) is an uncommon tumor of the salivary glands, with primary bronchogenic cases being particularly rare, especially in children. This report presents a case of a 3-year and 11-month-old boy who exhibited symptoms of cough and fever. Contrast-enhanced CT imaging revealed a solid mass in the right upper lung lobe accompanied by atelectasis, with poor bronchial visualization and no abnormal enhancement. Bronchoscopy identified a tumor obstructing the right upper lobe bronchial orifice. Surgical resection was performed, and histopathological analysis confirmed acinic cell carcinoma without lymph node involvement. The patient remained recurrence-free during an 18-month follow-up. Pediatric primary bronchial AciCC is exceptionally rare and typically manifests with non-specific symptoms. Radiological findings such as solid lung lesions or atelectasis may lead to misdiagnosis as pneumonia. However, complete surgical excision generally yields favorable outcomes.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-10-02
DOI
https://doi.org/10.3389/fonc.2025.1640216
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

Li Feng Tan, Songtao Bin, Jun Zhou, Ming Li et al.
Frontiers in Oncology
Salivary Gland Tumors Diagnosis and Treatment
article

Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

Li Feng Tan, Songtao Bin, Jun Zhou, Ming Li, Shu Yang, Jiaojiao Zhu, Yuxing Sun
article en

Abstract

Acinic cell carcinoma (AciCC) is an uncommon tumor of the salivary glands, with primary bronchogenic cases being particularly rare, especially in children. This report presents a case of a 3-year and 11-month-old boy who exhibited symptoms of cough and fever. Contrast-enhanced CT imaging revealed a solid mass in the right upper lung lobe accompanied by atelectasis, with poor bronchial visualization and no abnormal enhancement. Bronchoscopy identified a tumor obstructing the right upper lobe bronchial orifice. Surgical resection was performed, and histopathological analysis confirmed acinic cell carcinoma without lymph node involvement. The patient remained recurrence-free during an 18-month follow-up. Pediatric primary bronchial AciCC is exceptionally rare and typically manifests with non-specific symptoms. Radiological findings such as solid lung lesions or atelectasis may lead to misdiagnosis as pneumonia. However, complete surgical excision generally yields favorable outcomes.

Frontiers in OncologyVol. 15
Kunming Medical University (CN), Kunming Children's Hospital (CN)
Openalex Percentile: Top 57%
Salivary Gland Tumors Diagnosis and Treatment
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Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient — Li Feng Tan, Songtao Bin, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS