Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient
Acinic cell carcinoma (AciCC) is an uncommon tumor of the salivary glands, with primary bronchogenic cases being particularly rare, especially in children. This report presents a case of a 3-year and 11-month-old boy who exhibited symptoms of cough and fever. Contrast-enhanced CT imaging revealed a solid mass in the right upper lung lobe accompanied by atelectasis, with poor bronchial visualization and no abnormal enhancement. Bronchoscopy identified a tumor obstructing the right upper lobe bronchial orifice. Surgical resection was performed, and histopathological analysis confirmed acinic cell carcinoma without lymph node involvement. The patient remained recurrence-free during an 18-month follow-up. Pediatric primary bronchial AciCC is exceptionally rare and typically manifests with non-specific symptoms. Radiological findings such as solid lung lesions or atelectasis may lead to misdiagnosis as pneumonia. However, complete surgical excision generally yields favorable outcomes.
Authors
- Li Feng Tan (ORCID: https://orcid.org/0000-0003-1232-9308)
- Songtao Bin
- Jun Zhou (ORCID: https://orcid.org/0000-0002-2977-7839)
- Ming Li (ORCID: https://orcid.org/0000-0003-1114-8142)
- Shu Yang (ORCID: https://orcid.org/0000-0003-2864-9971)
- Jiaojiao Zhu (ORCID: https://orcid.org/0009-0009-6002-8957)
- Yuxing Sun
Institutions
- Kunming Medical University (CN)
- Kunming Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fonc.2025.1640216
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00