Liquid Chromatography–Tandem Mass Spectrometry Method for Simultaneous Quantification of Four Endocannabinoids and Endocannabinoid-Like Substances in Plasma: Application in an HIV—Hepatitis C Virus Coinfected Population
The study demonstrates that biological and technical factors markedly affect plasma EC and EC-like concentrations. Standardized preanalytical processing is therefore essential for accurate measurement, and the proposed method provides a robust tool for clinical and pharmacological research.
Authors
- Camille Richeval (ORCID: https://orcid.org/0000-0002-1234-5167)
- Jean‐Michel Gaulier (ORCID: https://orcid.org/0000-0003-1111-4671)
- Alexandr Gish (ORCID: https://orcid.org/0000-0002-3083-9304)
- Camélia Protopopescu (ORCID: https://orcid.org/0000-0003-0164-7917)
- Florian Hakim (ORCID: https://orcid.org/0000-0002-3335-6711)
- Tangui Barré (ORCID: https://orcid.org/0000-0002-3439-8868)
- Jean‐François Wiart
- Eqbal Radwan (ORCID: https://orcid.org/0000-0001-5720-095X)
- Delphine Allorge (ORCID: https://orcid.org/0000-0003-0297-3191)
- Patrizia Carrieri
Institutions
- Inserm (FR)
- Université de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Economic & Social Sciences, Health Systems & Medical Informatics (FR)
- Institut de Recherche pour le Développement (FR)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1097/ftd.0000000000001397
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00