Clinical association and potential molecular mechanisms of neonatal sepsis and necrotizing enterocolitis

This study suggests that neonatal sepsis may serve as a risk factor for NEC development through shared inflammatory pathways involving <i>FPR1</i>, <i>S100A12</i>, and <i>CSF3R</i>. These genes demonstrated diagnostic potential across both conditions and appear to mediate inflammatory processes involving immune cell recruitment. While these findings suggest new directions for early identification in high-risk infants, further clinical validation is necessary to confirm therapeutic implications.