Aerobic exercise improves clinical symptoms in people with Parkinson’s disease and its potential mechanism
Aerobic exercise has been shown to enhance both motor and non-motor functions in people with Parkinson's disease. The underlying mechanisms may involve the modulation of intestinal flora composition and diversity, bile acid metabolism, and inflammatory cytokine levels.
Authors
- Xinyu Wu (ORCID: https://orcid.org/0000-0002-1117-5098)
- Quan Wei (ORCID: https://orcid.org/0000-0002-0541-905X)
- Fengli Wang (ORCID: https://orcid.org/0000-0002-3461-6204)
- Chuanying Xu (ORCID: https://orcid.org/0009-0006-0851-9298)
- Hui Wang (ORCID: https://orcid.org/0000-0002-5208-8329)
- Yuning Liu (ORCID: https://orcid.org/0000-0002-9441-9667)
- Guiyun Cui (ORCID: https://orcid.org/0000-0002-1372-6391)
- Jie Xiang
Institutions
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fneur.2025.1658162
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- National Key Research and Development Program of China