Dihydromyricetin preserves β-cell function in type 1 diabetes via PI3K/AKT-mediated metabolic reprogramming
DMY, a readily accessible food-derived bioactive compound, reprograms lipid-inflammatory metabolism and activates PI3K/AKT to safeguard β-cell viability, highlighting its nutraceutical promise for dietary management of autoimmune diabetes.
Authors
- Haojie Huang (ORCID: https://orcid.org/0000-0003-2751-6413)
- Ta-Hui Lin (ORCID: https://orcid.org/0000-0001-7627-6095)
- Jeng-Yuan Yao (ORCID: https://orcid.org/0000-0002-8113-5710)
- Jia Li (ORCID: https://orcid.org/0000-0003-1500-869X)
- Lijia Li (ORCID: https://orcid.org/0000-0002-8774-7515)
- Jie Ren (ORCID: https://orcid.org/0000-0002-9711-7349)
Institutions
- Fujian Medical University (CN)
- Xiamen University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fnut.2025.1682308
- Primary Topic
- Medicinal plant effects and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00