Interleukin-40 and Oxidative Stress in Patients With Generalized Anxiety Disorder

This is the first study to explore the potential relationship between IL-40 and the pathophysiology of GAD. The observed elevation in IL-40 levels may reflect a possible immune regulatory imbalance in GAD. While these findings suggest that IL-40 could be a candidate biomarker for further investigation, their clinical utility for diagnosis or monitoring remains speculative. Additional large-scale and longitudinal studies are required to confirm these preliminary observations and to better understand the immunological aspects of GAD.