Effectiveness and safety of brivaracetam in comparison with levetiracetam in seizures
In summary, the study found that BRV is a safe alternative, with fewer and less severe side effects compared to LEV. While LEV showed slightly higher efficacy and a lower probability of drowsiness, BRV proved more tolerable for patients experiencing LEV-induced side effects. Switching from LEV to BRV decreased the psychiatric side effects.
Authors
- Kristen St. John (ORCID: https://orcid.org/0000-0001-7045-7485)
- Shalini Sivadasan (ORCID: https://orcid.org/0000-0002-4341-7063)
- S. Murugan (ORCID: https://orcid.org/0009-0003-0001-5317)
- Senthil Kumar Elumalai
- Flencinecia Basil Raj
- Stephy Susan Sam
Institutions
- Coimbatore Medical College and Hospital (IN)
- Kovai Medical Center and Hospital (IN)
Publication Details
- Journal
- Acta Epileptologica
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s42494-025-00229-z
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00