Relationship between serum ApoB-100 and lumbar bone mineral density in postmenopausal women: a retrospective analysis of a health screening population
ApoB-100 exhibits an independent negative association with lumbar BMD in postmenopausal women, partially mediated through inflammatory and platelet pathways. These findings support the potential utility of ApoB-100 as a biomarker for osteoporosis risk assessment in postmenopausal women, particularly within specific high-risk subgroups.
Authors
- Meilan Xue (ORCID: https://orcid.org/0000-0002-7296-0778)
- Fangfang Guo (ORCID: https://orcid.org/0000-0003-4245-998X)
- Qingwu Wu (ORCID: https://orcid.org/0000-0003-0943-2558)
- Yangyang Chen (ORCID: https://orcid.org/0009-0006-3864-1040)
- Hui Liu (ORCID: https://orcid.org/0000-0002-1093-1509)
- Shi-Li Gu
- HE Yu-hua
Institutions
- First Affiliated Hospital of Xinxiang Medical University (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fendo.2025.1667161
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Xinxiang Medical University