Anti-fatigue and antioxidative effects of amino acid (Leu, Gln, Cys)-EGCG complex via NRF2 and PGC-1α pathways: insights from cellular, animal, and pilot clinical studies
The AA-EGCG mixture enhances mitochondrial biogenesis and antioxidant capacity by activating the NRF2 and PGC-1α pathways, improving physical performance and reducing fatigue. This study highlights its potential as a supplement for managing fatigue and enhancing endurance.
Authors
- Sung‐Hee Han (ORCID: https://orcid.org/0000-0003-0825-6687)
- W.J. Lee (ORCID: https://orcid.org/0000-0002-3284-5425)
- Yeok Boo Chang
- Hyung Joo Suh (ORCID: https://orcid.org/0000-0001-8869-3929)
- Byoungkwon Kim
- Eun Young Jung (ORCID: https://orcid.org/0000-0002-1892-9809)
- Sang Min Kim
Institutions
- Korea University (KR)
- DNA Link (South Korea) (KR)
- Korea University (JP)
- Jeonju University (KR)
Publication Details
- Journal
- Nutrition Research and Practice
- Published
- 2025-01-01
- DOI
- https://doi.org/10.4162/nrp.2025.19.5.664
- Citations
- 1
- Primary Topic
- Muscle metabolism and nutrition
- Type
- article
- Field-Weighted Citation Impact
- 1.15