Seeded control of symmetry-directed diverse chiral π-stacked benzothiadiazole assemblies with leucine-based diamide units

Symmetrical and unsymmetrical incorporation of leucine-derived diamides with identical chirality into a benzothiadiazole-containing aryleneethynylene enables seeded control of three distinct chiral π-stacked assemblies. Theoretical studies indicate that the orientation of benzothiadiazole units contributes to this diversity, highlighting how substitution patterns and kinetic control program structurally ordered complexity in π-conjugated supramolecular systems.