Dynamin-Related Protein 1 and the NLRP3 Inflammasome in Parkinson's Disease: Mechanistic Insights and Therapeutic Opportunities
The Drp1-NLRP3 axis is one of the essential mechanistic connections between mitochondrial dynamics and neuroinflammation in PD. Focusing on this axis could offer novel therapeutic options, and advancing these approaches could pave the way for therapies that not only alleviate symptoms but also slow or halt the progression of the disease.
Authors
- K.L. Krishna (ORCID: https://orcid.org/0000-0001-7538-0798)
- Chethan Konasuru Someshwar
Institutions
- JSS Academy of Higher Education and Research (IN)
Publication Details
- Journal
- Current Molecular Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.2174/0115665240397746250915001750
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 0.00