Advances and Challenges in the Use of Biomechanics-Inspired Digital Technologies for Managing Pediatric Chronic Diseases: A Systematic

This study aims to systematically review biomechanics-inspired digital technologies applied in the management of pediatric chronic diseases, focusing on their effectiveness, limitations, and implementation challenges.Following PRISMA 2020 guidelines, a comprehensive search was conducted in Web of Science, Scopus, and Google Scholar. Studies were included if they addressed pediatric patients (0–18 years) and involved digital health interventions integrating biomechanical data or telemedicine solutions. A total of 20 peer-reviewed studies were selected after screening 368 records. Data extraction included study design, technologies, health outcomes, and implementation barriers. mHealth platforms demonstrated treatment adherence rates up to 80% in cystic fibrosis, while therapeutic video games improved quality of life and psychological well-being in pediatric cancer patients. Telemedicine significantly reduced hospitalization and improved follow-up attendance, particularly in diabetes and asthma cases. Advanced technologies, such as wearable motion sensors, robotic exoskeletons, and continuous glucose monitoring, enhanced rehabilitation outcomes and personalized treatment. Despite these benefits, barriers included high development costs, limited digital literacy, infrastructure gaps, and ethical concerns related to data privacy.Biomechanics-inspired digital technologies significantly enhance adherence, rehabilitation, and quality of life for children with chronic illnesses. However, widespread implementation requires addressing structural barriers, ensuring equitable access, and integrating culturally sensitive solutions. Future research should focus on adaptive tools, long-term evaluations, and strategies to bridge technological and socioeconomic gaps in pediatric healthcare.