Genome-wide methylation biomarkers and biological aging in patients with bipolar disorder characterized for lithium response
Our findings point to methylation patterns characterizing BD and support the hypothesis of accelerated cellular aging in BD.
Authors
- Federica Pinna (ORCID: https://orcid.org/0000-0002-3108-9509)
- Bernardo Carpiniello (ORCID: https://orcid.org/0000-0002-5385-7871)
- Massimo Gennarelli (ORCID: https://orcid.org/0000-0003-4192-945X)
- Lisa Buson (ORCID: https://orcid.org/0000-0003-1910-4232)
- Martina Pinna (ORCID: https://orcid.org/0000-0001-8636-9391)
- Marco Bortolomasi
- Donatella Congiu
- Alessio Squassina (ORCID: https://orcid.org/0000-0001-7415-7607)
- Mirko Manchia (ORCID: https://orcid.org/0000-0003-4175-6413)
- Maria Del Zompo (ORCID: https://orcid.org/0000-0001-9491-5938)
- Pasquale Paribello (ORCID: https://orcid.org/0000-0001-9953-6929)
- Giovanni Severino (ORCID: https://orcid.org/0000-0002-6354-2662)
- Claudia Pisanu (ORCID: https://orcid.org/0000-0002-9151-4319)
- Raffaella Ardau (ORCID: https://orcid.org/0000-0002-6420-5158)
- Martina Contu (ORCID: https://orcid.org/0009-0009-7549-8070)
- Alessandra Minelli (ORCID: https://orcid.org/0000-0002-9463-7808)
- Anna Meloni
- Caterina Chilllotti
Institutions
- Dalhousie University (CA)
- University of Cagliari (IT)
- Brescia University (US)
- Ospedale Santa Chiara (IT)
- Centro San Giovanni di Dio Fatebenefratelli (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Brescia (IT)
Publication Details
- Journal
- European Psychiatry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1192/j.eurpsy.2025.10112
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Cagliari
- Fondazione di Sardegna
- University of Cambridge
- Ministero della Salute
- Fidia Farmaceutici
- H. Lundbeck A/S