Determination of biochemical markers of altered hepatic metabolism in white rats exposed to X-rays

The article presents information about a study conducted to study changes in the level of enzymes and free products of lipid peroxidation in metabolic disorders in the liver of experimental animals exposed to X-ray radiation. The study was conducted on 42 intact white rats, which were divided into three groups. The first group (control) included 6 white rats. The second group included 18 intact white rats exposed to X-rays. In the third group, 10 days after the cessation of X-ray irradiation (18 animals), the level of liver enzymes in the blood was measured. Levels of lipid peroxidation (POL), malondialdehyde (MDA), diene conjugates (DC), hydrogen peroxide (H 2 O 2 ), creatine phosphokinase (CK), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), gamma-glutamyltransferase (GGT), aspartate aminotransferase (AST) were determined in the blood of experimental animals and alanine aminotransferase (ALT).