Do complex psychometric analyses really matter? Comparing multiple approaches using individual participant data from antidepressant trials
IRT and NA yielded negligible differences in effect outcomes relative to original trials. FA increased effect sizes and may be the most effective method for identifying the items on which placebo and treatment group outcomes differ.
Authors
- David Hevey (ORCID: https://orcid.org/0000-0003-2844-0449)
- Susan Brannick
- David F. Byrne (ORCID: https://orcid.org/0000-0002-0587-4677)
- Pim J. Cuijpers (ORCID: https://orcid.org/0000-0001-5497-2743)
- Robert M. Carney (ORCID: https://orcid.org/0000-0002-0737-6655)
- Emma K. Wallace (ORCID: https://orcid.org/0000-0002-9315-2956)
- Kenneth E. Freedland (ORCID: https://orcid.org/0000-0002-3118-9913)
- Suzanne Guérin (ORCID: https://orcid.org/0000-0002-6744-7590)
- Bishember Kathuria
- Frank Doyle (ORCID: https://orcid.org/0000-0002-3785-7433)
- Fiona Boland (ORCID: https://orcid.org/0000-0003-3228-0046)
- Alexandra L. Dima (ORCID: https://orcid.org/0000-0002-3106-2242)
Institutions
- University College Dublin (IE)
- Universitat Autònoma de Barcelona (ES)
- Trinity College Dublin (IE)
- University of Medicine and Health Sciences (KN)
- University College Cork (IE)
- Institute of Public Health (IE)
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
- Aware (United States) (US)
- Novartis (Ireland) (IE)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725101785
- Primary Topic
- Mental Health Research Topics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Irish Research Council