Association Between SIRT1 Gene Polymorphisms and Suicide Attempts in Schizophrenia: An Exploratory Study

Certain polymorphisms and haplotypes within the SIRT1 gene may be associated with suicide risk among patients with schizophrenia. These findings point to the potential role of genetic profiling in identifying high-risk individuals. Further large-scale studies are warranted to increase the generalizability of the findings and to elucidate the underlying mechanisms in greater detail.

Authors

Publication Details

Journal
Turkish Journal of Psychiatry
Published
2025-01-01
DOI
https://doi.org/10.5080/u27771
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between SIRT1 Gene Polymorphisms and Suicide Attempts in Schizophrenia: An Exploratory Study

Nadir Koçak, Ekrem Furkan Uçak, Memduha Aydın
Turkish Journal of Psychiatry
Tryptophan and brain disorders
article

Association Between SIRT1 Gene Polymorphisms and Suicide Attempts in Schizophrenia: An Exploratory Study

Nadir Koçak, Ekrem Furkan Uçak, Memduha Aydın
article en

Abstract

Certain polymorphisms and haplotypes within the SIRT1 gene may be associated with suicide risk among patients with schizophrenia. These findings point to the potential role of genetic profiling in identifying high-risk individuals. Further large-scale studies are warranted to increase the generalizability of the findings and to elucidate the underlying mechanisms in greater detail.

Turkish Journal of PsychiatryVol. 36
Openalex Percentile: Top 72%
Tryptophan and brain disorders
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Association Between SIRT1 Gene Polymorphisms and Suicide Attempts in Schizophrenia: An Exploratory Study — Nadir Koçak, Ekrem Furkan Uçak, et al. · Turkish Journal of Psychiatry (2025) | TGRS Research Map | TGRS