Naltrexone-bupropion for the treatment of binge eating disorder: a systematic review and meta-analysis

This meta-analysis found that naltrexone-bupropion has no significant benefits over placebo in reducing binge eating episodes or in improving metabolic or psychological outcomes. The possible effect on glycated hemoglobin levels warrants further investigation.

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Publication Details

Journal
Brazilian Journal of Psychiatry
Published
2025-01-01
DOI
https://doi.org/10.47626/1516-4446-2025-4258
Primary Topic
Eating Disorders and Behaviors
Type
article
Field-Weighted Citation Impact
0.00
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article

Naltrexone-bupropion for the treatment of binge eating disorder: a systematic review and meta-analysis

Milene Vitória Sampaio Sobral, Gilmara Peixoto Rister, Maurício Prätzel Ellwanger, Jordana Belgamasco Cavalcanti Marçal
Brazilian Journal of Psychiatry
Eating Disorders and Behaviors
article

Naltrexone-bupropion for the treatment of binge eating disorder: a systematic review and meta-analysis

Milene Vitória Sampaio Sobral, Gilmara Peixoto Rister, Maurício Prätzel Ellwanger, Jordana Belgamasco Cavalcanti Marçal
article en

Abstract

This meta-analysis found that naltrexone-bupropion has no significant benefits over placebo in reducing binge eating episodes or in improving metabolic or psychological outcomes. The possible effect on glycated hemoglobin levels warrants further investigation.

Brazilian Journal of PsychiatryVol. 47
Universidade do Oeste Paulista (BR), Universidade do Contestado (BR)
Openalex Percentile: Top 62%
Eating Disorders and Behaviors
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