Undiagnosed G6PD Deficiency in Black and Asian Individuals Is Prevalent and Contributes to Health Inequalities in Type 2 Diabetes Diagnosis and Complications
Undiagnosed G6PD deficiency has significant impact on T2D diagnosis with HbA1c and associates with increased risk of diabetes complications. This has major implications for global populations using HbA1c for diagnosis and monitoring, and could contribute significantly to inequalities in diabetes outcomes.
Authors
- Daniel G. MacArthur (ORCID: https://orcid.org/0000-0002-5771-2290)
- Chris Griffiths (ORCID: https://orcid.org/0000-0001-7935-8694)
- Gerome D. Breen (ORCID: https://orcid.org/0000-0003-2053-1792)
- Katherine Young (ORCID: https://orcid.org/0000-0003-2570-3864)
- David Collier (ORCID: https://orcid.org/0000-0003-4087-1559)
- Klaudia Walter (ORCID: https://orcid.org/0000-0003-4448-0301)
- Rohini Mathur (ORCID: https://orcid.org/0000-0002-3817-8790)
- Benjamin M. Jacobs (ORCID: https://orcid.org/0000-0002-6023-6010)
- Mohammed Bodrul Mazid
- David A. van Heel (ORCID: https://orcid.org/0000-0002-0637-2265)
- Julia Zöllner (ORCID: https://orcid.org/0000-0002-9072-9131)
- Teng Heng
- Stuart Rison (ORCID: https://orcid.org/0000-0003-3289-6668)
- Kamrul Islam (ORCID: https://orcid.org/0000-0002-5968-7068)
- Vladimir Ovchinnikov (ORCID: https://orcid.org/0000-0003-0350-8478)
- Caroline Winckley
- Susan F. Martin (ORCID: https://orcid.org/0000-0001-8746-0947)
- Michael A. Simpson (ORCID: https://orcid.org/0000-0002-8539-8753)
- Richard C. Trembath (ORCID: https://orcid.org/0000-0003-0550-3400)
- Dan Mason (ORCID: https://orcid.org/0000-0002-0026-9216)
- Sam Hodgson (ORCID: https://orcid.org/0000-0002-5610-850X)
- Caroline E Morton (ORCID: https://orcid.org/0000-0003-0783-0042)
- Ayat Salman (ORCID: https://orcid.org/0000-0002-7747-2757)
- Trevelyan J. McKinley (ORCID: https://orcid.org/0000-0002-9485-3236)
- Sabina Yasmin (ORCID: https://orcid.org/0000-0001-8399-1230)
- Shapna Hussain
- Miriam Samuel (ORCID: https://orcid.org/0000-0003-1258-435X)
- Saeed Bidi (ORCID: https://orcid.org/0000-0002-8951-2867)
- Omar Asgar
- Ji Chen
- John Solly
- Fabíola Eto (ORCID: https://orcid.org/0000-0002-0203-8649)
- Inês Barroso (ORCID: https://orcid.org/0000-0001-5800-4520)
- Claudia Langenberg (ORCID: https://orcid.org/0000-0002-5017-7344)
- Sheik Dowlut
- Andrew Tym Hattersley (ORCID: https://orcid.org/0000-0001-5620-473X)
- Elizabeth Owor
- Marie Spreckley (ORCID: https://orcid.org/0000-0002-8346-2408)
- Harry Green (ORCID: https://orcid.org/0000-0002-5105-184X)
- Veline L’Esperance (ORCID: https://orcid.org/0000-0003-3234-8987)
- Sarah Finer (ORCID: https://orcid.org/0000-0002-2684-4653)
- Asma Qureshi (ORCID: https://orcid.org/0000-0001-7857-8935)
- Moneeza K. Siddiqui (ORCID: https://orcid.org/0000-0001-9055-3896)
- Daniel Stow (ORCID: https://orcid.org/0000-0002-9534-4521)
- Hilary C. Martin (ORCID: https://orcid.org/0000-0002-4454-9084)
- Joanne E. Harvey (ORCID: https://orcid.org/0000-0001-5687-2586)
- William G. Newman (ORCID: https://orcid.org/0000-0002-6382-4678)
- Shabana Chaudhary
- Matt Hurles
- Ariadna González‐del Angel (ORCID: https://orcid.org/0000-0002-7096-0969)
- Ceri Durham
- Nishat Safa
- Grainne Colligan (ORCID: https://orcid.org/0000-0001-7357-2390)
- Panos Deloukas (ORCID: https://orcid.org/0000-0001-9251-070X)
- John Wright (ORCID: https://orcid.org/0000-0001-9572-7293)
- Joseph Gafton
- Sang Hyuck Lee (ORCID: https://orcid.org/0000-0002-5610-033X)
- Iaroslav Popov (ORCID: https://orcid.org/0000-0001-7538-123X)
- Ahsan Khan (ORCID: https://orcid.org/0000-0002-5189-6906)
- Shaheen Akhtar
- Raymond Chung (ORCID: https://orcid.org/0000-0003-0296-5546)
- Samina Ashraf (ORCID: https://orcid.org/0000-0002-3198-7245)
- Eamonn Maher
- Vivek Iyer (ORCID: https://orcid.org/0000-0003-4451-8293)
- Jessry Russell
- Amna Asif
- Alys M. Ridsdale
- Karen Tricker
- Hazera Khatun
- Karen A. Hunt (ORCID: https://orcid.org/0000-0002-2164-6412)
- Jan Whalley
- Georgios Kalantzis
- Ishevanhu Zengeya
- Emily Mantle
Institutions
- Queen Mary University of London (GB)
- University of Exeter (GB)
- NIHR Exeter Clinical Research Facility (GB)
Publication Details
- Journal
- Diabetes Care
- Published
- 2025-09-29
- DOI
- https://doi.org/10.2337/dc25-0556
- Citations
- 5
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 17.47
Funders
- Bristol-Myers Squibb
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Alnylam Pharmaceuticals
- Queen Mary University of London
- Royal Devon and Exeter NHS Foundation Trust
- Broad Institute
- Barts Charity
- Maze Therapeutics
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Exeter
- King's College London
- Public Health England
- Novo Nordisk
- Barts Health NHS Trust
- Medical Research Council
- Engineering and Physical Sciences Research Council
- Economic and Social Research Council
- NIHR School for Primary Care Research