Cerebral Sinovenous Thrombosis in Children With Acute Bacterial Intracranial Infection
CSVT is common in children with acute bacterial intracranial infection but difficult to clinically identify. Clinicians should maintain a high index of suspicion for CSVT in this population and consider appropriate screening imaging studies, particularly in children with mastoiditis, cerebritis, extra-axial focal suppurative infection, and/or dehydration. Anticoagulation was well-tolerated in this cohort; further studies should focus on determining its safety, benefit, and ideal duration in infection-related CSVT.
Authors
- Jennifer L. McGuire (ORCID: https://orcid.org/0000-0002-8245-7199)
- Rebecca Ichord (ORCID: https://orcid.org/0000-0002-6863-0274)
- Kathleen Chiotos (ORCID: https://orcid.org/0000-0002-0204-8708)
- Sanjeev Swami (ORCID: https://orcid.org/0000-0001-9962-0354)
- Aleksandra S. Dain (ORCID: https://orcid.org/0000-0003-3003-890X)
- Lauren A. Beslow (ORCID: https://orcid.org/0000-0003-0571-980X)
- Leah Loerinc (ORCID: https://orcid.org/0000-0002-5671-645X)
- Nehali Mehta (ORCID: https://orcid.org/0000-0003-4261-250X)
- Nakul Sheth
- Claudia Gambrah-Lyles (ORCID: https://orcid.org/0000-0002-2448-2265)
- Mark Halverson (ORCID: https://orcid.org/0000-0003-0039-708X)
Institutions
- Children's Hospital of Philadelphia (US)
- Nemours Children's Clinic (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1212/wnl.0000000000214175
- Citations
- 3
- Primary Topic
- Cerebral Venous Sinus Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 4.17