[Therapeutic potential of extracellular vesicles in neurological diseases].

Extracellular vesicles (EVs), nanoscale lipid bilayer vesicles actively secreted by organisms into the extracellular environment, are rich in specific bioactive substances, such as proteins, genetic materials and lipids. These vesicles are involved in intercellular interactions and can pass through the blood-brain barrier, and may thus potentially serve as important biological substances for treatment of neurological diseases. In this review, we summarize the biological origin of EVs and their therapeutic potential in neurological diseases, expound the possibility of EV-based treatment of neurological diseases using traditional Chinese medicine, and discuss the challenges and prospects of researches of EVs for the treating neurological diseases.

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Publication Details

Journal
PubMed
Published
2025-09-29
DOI
https://doi.org/10.12122/j.issn.1673-4254.2025.09.24
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

[Therapeutic potential of extracellular vesicles in neurological diseases].

Ting Wang, Qin Du, Xueqing Xia, Chao Yang
PubMed
Extracellular vesicles in disease
article

[Therapeutic potential of extracellular vesicles in neurological diseases].

Ting Wang, Qin Du, Xueqing Xia, Chao Yang
article en

Abstract

Extracellular vesicles (EVs), nanoscale lipid bilayer vesicles actively secreted by organisms into the extracellular environment, are rich in specific bioactive substances, such as proteins, genetic materials and lipids. These vesicles are involved in intercellular interactions and can pass through the blood-brain barrier, and may thus potentially serve as important biological substances for treatment of neurological diseases. In this review, we summarize the biological origin of EVs and their therapeutic potential in neurological diseases, expound the possibility of EV-based treatment of neurological diseases using traditional Chinese medicine, and discuss the challenges and prospects of researches of EVs for the treating neurological diseases.

PubMedVol. 45(9)
Third Affiliated Hospital of Southern Medical University (CN), Southern Medical University (CN)
Openalex Percentile: Top 76%
Extracellular vesicles in disease
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