External limiting membrane defects in age‐related macular degeneration. The Beijing Eye Study

The spatial correlation between ELM defects and EZ defects, the associations of both defect types with a higher occurrence of iHRFs superior to the ELM, the association between an absence of ELM defects and a higher prevalence of iHRFs located inferior to the ELM, and the association between a higher ELM defect prevalence and higher IZT prevalence may suggest the ELM/EZ may act as a barrier for RPE cells migrating into the retina.

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Publication Details

Journal
Acta Ophthalmologica
Published
2025-09-29
DOI
https://doi.org/10.1111/aos.70015
Primary Topic
Retinal Imaging and Analysis
Type
article
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article

External limiting membrane defects in age‐related macular degeneration. The Beijing Eye Study

Rahul Arvo Jonas, Ya Xing Wang, Jost Bruno Jonas, Jie Xu et al.
Acta Ophthalmologica
Retinal Imaging and Analysis
article

External limiting membrane defects in age‐related macular degeneration. The Beijing Eye Study

Rahul Arvo Jonas, Ya Xing Wang, Jost Bruno Jonas, Jie Xu, Songhomitra Panda‐Jonas
article en

Abstract

The spatial correlation between ELM defects and EZ defects, the associations of both defect types with a higher occurrence of iHRFs superior to the ELM, the association between an absence of ELM defects and a higher prevalence of iHRFs located inferior to the ELM, and the association between a higher ELM defect prevalence and higher IZT prevalence may suggest the ELM/EZ may act as a barrier for RPE cells migrating into the retina.

Acta Ophthalmologica
Beijing Tongren Hospital (CN), Chinese University of Hong Kong (HK), University of Cologne (DE), Capital Medical University (CN), Heidelberg University (DE), Institut Français (FR), Singapore National Eye Center (SG), New York Eye and Ear Infirmary (US), L V Prasad Eye Institute (IN), Fondation de Rothschild (FR), Beijing Tsinghua Chang Gung Hospital (CN), University Hospital Cologne (DE), Icahn School of Medicine at Mount Sinai (US), Tsinghua University (CN)
Openalex Percentile: Top 60%
Retinal Imaging and Analysis
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