Therapeutic outcomes and predictors of efficacy for endoscopic variceal ligation plus propranolol in liver cirrhosis-related upper gastrointestinal bleeding

The EVL plus propranolol regimen demonstrates significant efficacy in treating UGIB in cirrhosis, outperforming EVL alone in improving hemodynamics (PVF/SVF), shortening hemostasis and hospitalization duration, and reducing rebleeding rates. Moreover, advanced age, prolonged disease duration, and longer bleeding times are independent risk factors for poor therapeutic outcomes.

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Publication Details

Journal
World Journal of Gastrointestinal Surgery
Published
2025-09-23
DOI
https://doi.org/10.4240/wjgs.v17.i9.109152
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
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article

Therapeutic outcomes and predictors of efficacy for endoscopic variceal ligation plus propranolol in liver cirrhosis-related upper gastrointestinal bleeding

Long Cheng, Danfeng Gong
World Journal of Gastrointestinal Surgery
Liver Disease and Transplantation
article

Therapeutic outcomes and predictors of efficacy for endoscopic variceal ligation plus propranolol in liver cirrhosis-related upper gastrointestinal bleeding

Long Cheng, Danfeng Gong
article en

Abstract

The EVL plus propranolol regimen demonstrates significant efficacy in treating UGIB in cirrhosis, outperforming EVL alone in improving hemodynamics (PVF/SVF), shortening hemostasis and hospitalization duration, and reducing rebleeding rates. Moreover, advanced age, prolonged disease duration, and longer bleeding times are independent risk factors for poor therapeutic outcomes.

World Journal of Gastrointestinal SurgeryVol. 17(9)
The First People's Hospital of Changde (CN)
Openalex Percentile: Top 64%
Liver Disease and Transplantation
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