Bone marrow mesenchymal stem cell-derived exosomal lactate dehydrogenase A promotes tendon-bone healing <i>via</i> histone lactylation-mediated cartilage regeneration
LDHA in BMSC-Exos promotes BMP7 expression <i>via</i> H3K18 lactylation modification, which further promotes tendon-bone healing after ACLR.
Authors
- Kaifeng Gan (ORCID: https://orcid.org/0000-0002-5166-6377)
- Ting Zhang (ORCID: https://orcid.org/0000-0001-6911-6333)
- Qing Huang (ORCID: https://orcid.org/0000-0002-8884-2063)
Institutions
- Ningbo Medical Center Lihuili Hospital (CN)
- Ningbo University Affiliated Hospital (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-09-24
- DOI
- https://doi.org/10.4252/wjsc.v17.i9.106282
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00