18F-PSMA-1007 and 18F-FDG PET/CT Findings of Pulmonary Tuberculosis Mimicking Malignancy

A 78-year-old man with hormone-sensitive metastatic prostate cancer underwent chest CT, which revealed a gradually enlarging pulmonary nodule in the left upper lobe, suggestive of lymphangitic metastasis. To further evaluate the lesion, both 18 F-FDG and 18 F-PSMA-1007 PET/CT were performed. The lesion showed intense FDG uptake but relatively low PSMA uptake, raising the suspicion of a primary lung malignancy. Histopathologic examination after wedge resection confirmed pulmonary tuberculosis.