An Adaptive Approach to Recurrent Pseudomonas Cellulitis and Bacteremia in Patients with Comorbid Complexities

Pseudomonas aeruginosa has become increasingly difficult to manage due to its acquired antibiotic resistance and patient specific complications. The objective of this case study was to help guide management of resistant Pseudomonas in patients with complex comorbidities such as chronic kidney disease, recurrent cellulitis, venous insufficiency and more. Initial measures for treatment included Ciprofloxacin, Doxycycline, Levofloxacin and Vancomycin, but the patient either responded poorly with recurrent infections or did not respond at all to the treatment regiments. The patient felt relief and held the longest period of resolution when the treatment regimen included Daptomycin and Meropenem.