A Case Report on the Treatment of Hyperthyroidism in Schizophrenia Comorbidity with Traditional Chinese and Western Medicine

Objective: To explore the clinical application value and ideas of the collaborative mode of traditional Chinese and Western medicine based on syndrome differentiation and treatment in the treatment of complex schizophrenia. Methods: the diagnosis and treatment process of a 53 year old female patient with schizophrenia comorbid hyperthyroidism was reported in detail. The patient had a history of 25 years, was intolerant to a variety of antipsychotics and had repeated symptoms. A small dose of olanzapine (5mg/day) combined with escitalopram oxalate (10mg/day) was used. According to the syndrome differentiation of traditional Chinese medicine, the treatment was divided into three stages: the first diagnosis (liver depression and phlegm disturbance, heart and spleen deficiency) was treated with soothing liver depression, resolving phlegm and opening orifices, invigorating spleen and benefiting qi, and Chaihu Shugan powder combined with Wendan Decoction was used as the decoction; The second diagnosis (liver and kidney deficiency, spleen and stomach weakness) is to nourish the liver and kidney, strengthen the spleen and appetizer; Three diagnostic methods (deficiency Yang floating over, phlegm heat internal disturbance) are used to calm nerves, clear away heat and dissipate phlegm. Results: after treatment, the patients' positive symptoms such as hallucination and delusion disappeared, the hyperthyroidism related physical symptoms and drug side effects were significantly improved, and the condition was stable. Conclusion: this case shows that the dynamic syndrome differentiation of traditional Chinese medicine based on the principle of "corresponding prescriptions and syndromes" can effectively cooperate with western medicine, significantly improve the physical symptoms and drug side effects of patients while controlling mental symptoms, reflecting the synergistic advantages of traditional Chinese medicine and Western medicine of "dynamic syndrome differentiation, simultaneous treatment of physical diseases, synergy and detoxification".