Impact of Seasonal Variability in Nasal Nitric Oxide Measurements for Primary Ciliary Dyskinesia Screening

Nasal NO levels exhibited seasonal variability, with statistically significant lower values during winter. Although most measurements remained within normal limits, there were many more abnormally low levels during winter, most of which normalized during summer. Therefore, repeat testing in another season, preferably summer, is recommended to ensure accurate PCD screening and avoid unnecessary invasive tests.

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Publication Details

Journal
Respiratory Care
Published
2025-09-29
DOI
https://doi.org/10.1177/19433654251378049
Citations
1
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
1.16
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Impact of Seasonal Variability in Nasal Nitric Oxide Measurements for Primary Ciliary Dyskinesia Screening

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1.16
article

Impact of Seasonal Variability in Nasal Nitric Oxide Measurements for Primary Ciliary Dyskinesia Screening

Einat Shmueli, Dario Prais, Hagit Levine, Miri Dotan, O. Baron, Ori Goldberg, Eyal Jacobi, Meir Mei‐Zahav, Patrick Stafler, Lior Tsviban
article en
1 citations

Abstract

Nasal NO levels exhibited seasonal variability, with statistically significant lower values during winter. Although most measurements remained within normal limits, there were many more abnormally low levels during winter, most of which normalized during summer. Therefore, repeat testing in another season, preferably summer, is recommended to ensure accurate PCD screening and avoid unnecessary invasive tests.

Respiratory CareVol. 71(2)
Tel Aviv University (IL), Kaplan Medical Center (IL), Schneider Children's Medical Center (IL)
Openalex Percentile: Top 17%
Asthma and respiratory diseases
1.16
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