Immunohistochemical Characterization of <scp>JAK</scp> Family Expression in the Primary Inflammatory Infiltrate of Lichen Planopilaris and Folliculitis Decalvans, With an Exploratory Clinical Assessment of Oral <scp>JAK</scp> Inhibitors
JAK3 and TYK2 were overexpressed in LPP and FD samples compared to healthy controls, supporting JAKs as potential pharmacological targets of interest. JAKis could be an effective and safe treatment for LPP patients.
Authors
- Giuseppe Gallo (ORCID: https://orcid.org/0000-0001-8390-4467)
- Rosa García-Martín
- Simone Ribero (ORCID: https://orcid.org/0000-0002-0098-1406)
- Antonio Sahuquillo‐Torralba
- Rodolfo David Palacios‐Diaz (ORCID: https://orcid.org/0000-0002-8353-7481)
- Rafael Botella‐Estrada (ORCID: https://orcid.org/0000-0002-6153-8192)
- Ricardo Ruíz‐Villaverde (ORCID: https://orcid.org/0000-0002-0381-6174)
- Jerry Shapiro (ORCID: https://orcid.org/0000-0002-2971-1223)
- Mar Blanes‐Martínez
- Kristen I. Lo Sicco
- M. Rodríguez‐Serna (ORCID: https://orcid.org/0000-0002-2690-3668)
- Federica Gelato (ORCID: https://orcid.org/0000-0002-7028-0322)
- Alejandro Lobato‐Berezo (ORCID: https://orcid.org/0000-0001-8725-3999)
- María Garrido-Ruiz
- Margarita Llavador‐Ros
- Rocío Gil‐Redondo (ORCID: https://orcid.org/0000-0003-3794-0402)
- Vicent Martínez‐Cózar (ORCID: https://orcid.org/0000-0001-5383-3346)
- Begoña Escutia‐Muñoz
- Conrad Pujol‐Marco (ORCID: https://orcid.org/0009-0000-0345-7485)
- Jorge Magdaleno‐Tapial (ORCID: https://orcid.org/0000-0003-0046-6962)
- José Luis Rodríguez‐Peralto (ORCID: https://orcid.org/0000-0002-6578-7153)
- Virginia Velasco‐Tamariz (ORCID: https://orcid.org/0000-0003-4009-0525)
- Miguel Antonio Lasheras‐Pérez (ORCID: https://orcid.org/0000-0001-7429-9592)
- Irene Albert‐Cobo
- Nicolay S. Pantoja Borja
Institutions
- Universidad Complutense de Madrid (ES)
- Universitat de València (ES)
- Hospital Universitario La Paz (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- International Olive Council (ES)
- Research Institute Hospital 12 de Octubre (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Leitat Technological Center (ES)
- Hospital General Universitario De Valencia (ES)
- Hospital Del Mar (ES)
- Hospital General Universitario de Alicante Doctor Balmis (ES)
- University of Turin (IT)
- New York University (US)
Publication Details
- Journal
- International Journal of Dermatology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1111/ijd.70084
- Citations
- 1
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.84