Soluplus - solid dispersion for enhanced drug delivery
Many drugs have poor water solubility, which reduces their effectiveness. Solid dispersions are used to enhance the dissolution of such drugs. Soluplus, a polymer, improves drug solubility, prevents crystallization, and enhances absorption. It can be incorporated using techniques such as hot-melt extrusion, spray drying, and solvent evaporation. Incorporating Soluplus in solid dispersions improves drug performance and facilitates better bioavailability.
Authors
- Karumoju Navya
- Vinod Kumar K (ORCID: https://orcid.org/0000-0002-0949-7821)
- Sultanova N.D.
- A Triveni
- B Vikasitha
Institutions
- Dorset HealthCare University NHS Foundation Trust (GB)
Publication Details
- Journal
- UPI Journal of Pharmaceutical Medical and Health Sciences
- Published
- 2025-09-29
- DOI
- https://doi.org/10.37022/jpmhs.v8i3.147
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00