Improved Survival with Improved NAPRC Compliance: A Single-Institution Experience

<b>Background:</b> The National Accreditation Program for Rectal Cancer (NAPRC) was developed in 2017. This study investigates three-year survival after diagnosis of rectal cancer as a function of compliance with NAPRC standards. <b>Methods:</b> A prospective database recorded compliance with 15 NAPRC standards for patients diagnosed August 2019 through August 2021. This database was retrospectively reviewed for compliance and three-year survival after diagnosis. <b>Results:</b> Three groups were identified (low, moderate, and high compliance) without significant difference in age (<i>p</i> = 0.662), sex (<i>p</i> = 0.919), race (<i>p</i> = 0.88), or disease stage (<i>p</i> = 0.166) between groups. Compared to the least compliant group, both moderate- and high-compliance groups had statistically significant lower hazard ratios (HR 0.22 and HR 0.12, respectively). <b>Conclusions:</b> Increased compliance led to a significant survival benefit. Rectal cancer patients who received care adherent to at least eight components of the NAPRC standards had a significant survival benefit three years after diagnosis compared to patients with less compliance.