Photo-induced ruthenium-catalyzed alkene C–H-arylation at room temperature
C-H arylation has surfaced as a powerful tool for molecular sciences, with alkene C-H arylation thus far requiring either high reaction temperatures of 120 °C or stoichiometric amounts of RMgX. In sharp contrast, we herein report on room-temperature C-H arlyations of alkenes by means of ruthenium(II) catalysis with ample scope. This strategy also enabled late-stage diversification of structurally complex molecules and mechanistic studies provided strong evidence for photo-excitation of a ruthenacycle intermediate.
Authors
- Tanumoy Mandal
- Lutz Ackermann (ORCID: https://orcid.org/0000-0001-7034-8772)
- Sven Trienes (ORCID: https://orcid.org/0009-0008-8910-7459)
- Stéphane Golling
Institutions
- German Centre for Cardiovascular Research (DE)
- University of Göttingen (DE)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04527d
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Zentrum für Herz-Kreislaufforschung
- Deutscher Akademischer Austauschdienst
- Deutsche Forschungsgemeinschaft
- Gottfried Wilhelm Leibniz Universität Hannover
- Leibniz-Gemeinschaft